Szerző:  Mohamed Faizal Abdul-Careem

Kiadó: EDRA / SERVET

Nyelv: Angol

ISBN:  9788416315017

Megjelenés:  2013

Oldalszám:  80

Kötés: Keménytáblás-cérnafűzött

Illusztrációk: Színes fényképek, táblázatok, diagramok és rajzok

LEÍRÁS:

MD is a lymphomatous and neuropathic disease of domestic birds caused by an alphaher-pesvirus. Fowls get infected by inhalation of infected dust from the poultry houses and the virus is shed from the feather follicle of infected birds. Chickens are the most important natural hosts for MD, which usually takes place at 12-30 weeks of age. Besides, MD is one of the most ubiquitous avian infections. It has been reported in chicken flocks worldwide. Every flock, except those maintained under strict pathogen-free conditions, is presumed to be infected. MD may cause important economic losses through a subclinical decrease in growth rate and egg production. Clinical signs observed include paralysis of the legs and wings and enlargement of peri-pheral nerves. Moreover, chickens may become persistently infected without developing clinical disease. According to the current situation, it is necessary to review and update this severe and widespread problem. To make it easier, the author, a prestigious specialist in this field, has developed a thorough assessment of this topic in a didactic and visual way. Many resour-ces (images, tables, graphs, etc.) have been included to facilitate the comprehension of this disease by the reader. This precise and straightforward information will help the vete-rinarians to know everything about this condition and tackle it properly.

1. Introduction

General definition

Synonyms

Economic significance

History

2. Aetiology

The virus, MDV

Taxonomy

Morphology

MDV evolution

3. Epidemiology

Hosts

Age distribution

Geographic distribution

Environmental persistence

Transmission

Incubation period

Incidence

Mortality

4. Pathogenesis

MDV pathogenesis cycle

Events at respiratory mucosa

Events at bursa of Fabricius

Events at FFE

Latency, transformation and lymphoma

formation

Immunosuppression

5. Clinical manifestations

Clinical manifestations

Nonspecific signs

Transient paralysis

Lymphomas

Other neurological manifestations

Immunosuppression

6. Immunity

Immunity

Innate host responses

Adaptive host responses

7. Diagnosis

Diagnosis

History and clinical signs

Gross postmortem lesions

Histological changes

Immunological techniques

Antibody detection methods (serology)

Antigen detection methods

Virus isolation in cell cultures

Molecular techniques

8. Prevention and control

Control by vaccination

Available vaccines

Hatchery vaccination

Mechanism of protection

Vaccination failure

Management control

Biosecurity

Cleaning and disinfection

Genetic control

9. References