Preface ix

Acknowledgments x

Section A: Pharmacology Guidelines

1 Understanding Minimum Inhibitory Concentrations (MICs) 1

2 Static versus Cidal Antibiotics 1

3 In Vitro versus In Vivo Efficacy 2

4 Approaching Infectious Disease Cases 2

5 Why Antibiotics Fail 4

6 Adjusting Doses in Renal Failure 5

7 Pregnancy Risk Categories 6

8 Lactation Guidelines: Penetration of Drugs into Milk 7

9 Safe Writing Skills 7

10 Basic Math Skills 8

Section B: Empiric Therapy Pending Diagnostic Results

11 Arthritis Osteomyelitis 9

12 Bacteremia and Sepsis 10

13 Central Nervous System Infections (Meningitis) 11

14 Endocarditis (Bacterial) 12

15 Intra-Abdominal Infections 13

16 Neonatal Infections 14

17 Infections Associated with Neutropenia 15

18 Otitis Externa and Otitis Media 15

19 Pancreatitis 16

20 Peritonitis and Abscesses 17

21 Pneumonia/Bronchitis 18

22 Prostatitis 19

23 Pyothorax Infections 20

24 Sinus Infections 20

25 Skin and Soft Tissue Infections 21

26 Urinary Tract Infections 22

Section C: Therapy of Established Infections

27 Acanthamoeba 25

28 Acinetobacter 26

29 Actinomyces 27

30 Adenovirus (Infectious Canine Hepatitis) 28

31 Aelurostrongylus Abstrusus (Feline Lungworm) 29

32 Anaerobic Species (Bacteroides and Provotella) 30

33 Anaplasma Species 30

34 Ancylostoma Species (Hookworms) 31

35 Ascaris Species (Roundworms) 32

36 Aspergillus Species 33

37 Babesia Species 35

38 Bartonella Species (Cat Scratch Disease) 36

39 Blastomycosis 37

40 Bordetella Bronchiseptica (Kennel Cough) 38

41 Borrelia Burgdorferi (Lyme Disease) 39

42 Brucella (Canine Brucellosis) 40

43 Calicivirus 42

44 Campylobacter Species 43

45 Candida Species 43

46 Canine Influenza Virus (CIV) 44

47 Capillaria Aerophila (Lungworm) 45

48 Cestode Species (Tapeworms) 46

49 Cheyletiella Species (Walking Dandruff) 47

50 Chlamydia Species 48

51 Citrobacter Species 49

52 Clostridium Difficile 50

53 Clostridium Tetani/Botulinum 51

54 Coccidiomycosis 52

55 Corynebacterium Species 53

56 Coxiellosis Species (Q Fever) 54

57 Cryptococcus Species 55

58 Cryptosporidium Species 56

59 Ctenocephalides Species (Fleas) 56

60 Cuterebra Species (Botfly Larvae) 57

61 Cytauxzoon Felis 59

62 Dematiaceous Fungi (Phaeohypomycosis Chromoblastomycosis) 59

63 Demodex Canis/Felis (Red Mange) 60

64 Dermatophytosis 61

65 Dipylidium Caninum (Flea Tapeworm) 62

66 Dirofilaria Immitis (Heartworm) 63

67 Distemper (Canine) 64

68 Ehrlichia Species 65

69 Entamoeba Histolytica 66

70 Enterobacter Species 67

71 Enterococcus 68

72 Erysipelothrix Species 69

73 Escherichia Coli (Enterotoxigenic/Enterohemorrhagic) 70

74 Eschericha Coli (Nonenterohemorrhagic) 71

75 Feline Coronovirus (Feline Infectious Peritonitis: FIP) 72

76 Feline Immunodeficiency Virus (FIV) 73

77 Feline Leukemia Virus (FeLV) 74

78 Feline Panleukopenia Virus 75

79 Francisella Tularensis (Tularemia) 75

80 Fusarium Species 76

81 Giardia Species 77

82 Helicobacter Species 78

83 Hepatozoon Americanum/Canis (Hepatozoonosis) 79

84 Herpes Virus (Canine) 80

85 Histoplasma Capsulatum 80

86 Hyalohyphomycosis (Paecilomyces/Scedosporium) 81

87 Isospora Species 82

88 Klebsiella Species 83

89 Leishmaniosis 84

90 Leptospira Species 85

91 Lice 86

92 Malassezia 87

93 Microsporidia 88

94 Mucor Species 89

95 Mycobacterium Species 90

96 Mycoplasma Species 91

97 Myiasis (Maggots) 92

98 Neospora Caninum 92

99 Neorickettsia Helminthoeca 93

100 Nocardia Species 94

101 Otodectes Cynotis (Otodectic Mange) 95

102 Papilloma Virus 96

103 Paragonimus Species (Liver Flukes) 97

104 Parvovirus 97

105 Pasteurella Species 98

106 Poxvirus 99

107 Proteus Species 100

108 Prototheca Species 101

109 Pseudomonas Aeruginosa 102

110 Pseudorabies (Aujeszky’s Disease) 103

111 Rabies Virus 104

112 Rhodococcus Equi 104

113 Rickettsia Rickettsii (Rocky Mountain Spotted Fever) 105

114 Salmonella Species 106

115 Sarcoptes Scabiei (Sarcoptic Mange) 107

116 Serratia Species 108

117 Shigella Species 109

118 Sporothrix Species 110

119 Staphylococcus Species 111

120 Streptococcus Species 112

121 Strongyloides Species (Threadworms) 113

122 Toxocara Canis/Cati 114

123 Toxoplasma Gondii (Toxoplasmosis) 115

124 Trichomonas Species 115

125 Yersinia Pestis (Plaque) 116

Section D: Antibiotics

126 Amikacin 118

127 Amoxicillin 120

128 Ampicillin 122

129 Azithromycin 124

130 Cefadroxil 126

131 Cefazolin 128

132 Cefdinir 130

133 Cefepime 132

134 Cefotaxime 134

135 Cefovecin 136

136 Cefoxitin 138

137 Cefpodoxime 140

138 Ceftazidime 142

139 Ceftiofur 143

140 Cefuroxime 145

141 Cephalexin 147

142 Chloramphenicol 149

143 Ciprofloxacin 151

144 Clarithromycin 153

145 Clavamox 155

146 Clindamycin 157

147 Dicloxacillin 159

148 Doxycycline 161

149 Enrofloxacin 163

150 Erythromycin 166

151 Florfenicol 168

152 Gentamicin 170

153 Imipenem and Cilastatin 172

154 Linezolid 174

155 Marbofloxacin 176

156 Meropenem 178

157 Metronidazole 180

158 Minocycline 182

159 Nitrofurantoin 185

160 Orbifloxacin 187

161 Oxytetracycline 189

162 Penicillin 191

163 Pradofloxacin 193

164 Rifampin 195

165 Potentiated Sulfas 197

166 Timentin 200

167 Tobramycin 202

168 Tylosin 204

169 Unasyn 206

170 Vancomycin 208

171 Zosyn 211

Section E: Antifungal Agents

172 Amphotericin B 221

173 Caspofungin 224

174 Clotrimazole 226

175 Enilconazole 228

176 Fluconazole 230

177 Flucytosine 232

178 Itraconazole 234

179 Ketoconazole 237

180 Posaconazole 239

181 Terbinafine 241

182 Voriconazole 243

Section F: Antiparasitic Agents

183 Albendazole 247

184 Atovaquone 249

185 Fenbendazole 251

186 Fipronil 253

187 Imidacloprid 255

188 Imidocarb Dipropionate 257

189 Ivermectin 259

190 Lufenuron 262

191 Meglumine Antimoniate 263

192 Melarsomine 265

193 Miltefosine 268

194 Milbemycin Oxime 269

195 Moxidectin 272

196 Nitazoxanide 274

197 Nitenpyram 276

198 Ponazuril (Toltrazuril Sulfone) 278

199 Praziquantel 280

200 Primaquine Phosphate 282

201 Pyrantel Pamoate 283

202 Ronidazole 285

203 Selamectin 287

204 Spinosid 289

205 Sulfadimethoxine 291

206 Tinidazole 294

Section G: Antiviral Agents

207 Acyclovir 297

208 Famciclovir 299

209 Cidofovir 301

210 Idoxuridine 302

211 Oseltamivir 304

212 Vidarabine 306

213 Zidovudine 307

Index 310

“Overall, I found this book to be a useful clinical handbook well worth the price. It is recommended as a practical clinical reference for small animal practitioners with limited experience in the area of infectious disease or veterinary students interested in learning clinical information necessary to effectively treat dogs and cats with common infectious diseases.”  (Journal of the American Veterinary Medical Association, 15 December 2015)

“A very useful tool to enrich whatever formulary may be lying in the consulting room.”  (Vet Nurses Today, 1 October 2015)

"This book is quite unique in its systematic and logic structure and is a welcome addendum to current literature in this topic." (EJCAP 2016)

"From diagnosis and dosages to risk factors and resources for further reading in professional veterinary publications, all the guidelines and details are written with clinical settings in mind, making this a top office pick." (Midwest Book Review 2016)